Sarah A. Tishkoff

2001 Fellow

Fellowship Institution: University of Maryland, College Park

Current Institution: University of Pennsylvania

Biological Sciences

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About Sarah A. Tishkoff's Work

My group uses a highly interdisciplinary approach (integrating field work in Africa, empirical and computational analyses) to study human population genetics, human evolution, the genetic basis of adaptation, and genetic and environmental factors influencing variable anthropometric, cardiovascular, metabolic, and immune-related traits. Our research focuses primarily on African population variation, a region that has been underrepresented in human genomic studies. Together with our African collaborators, we have compiled an extensive DNA database, representing more than 10,000 Africans from ~200 ethnic groups. Our research group uses an integrative genomics approach, combining genomic, proteomic, epigenomic, transcriptomic, metabolomic, and microbiome data to understand the genetic and environmental factors influencing complex human traits, including disease susceptibility. This research can affect a wide range of biomedical issues – for example, why humans have different susceptibility to disease, how they metabolize food and drugs, and how they adapt to changes in environment.


Awards and Achievements

Burroughs/Wellcome Fund Career Award in the Biomedical Sciences (1998-2003)

David and Lucile Packard Career Award in Science and Engineering (2001-2006)

Penn Integrates Knowledge (PIK) University Endowed Chair, University of Pennsylvania (2008)

NIH Pioneer Award 2013 Semi-Finalist for HHMI Investigator Competition (2013)

National Academy of Sciences


In the News

Interview with Sarah Tishkoff, PhD
HHMI BioInteractive

Out of Africa: Startling New Genetics of Human Origins
Scientific American

African's have world's greatest genetic variation
NBC News

Drink Milk in Africa? Genes Behind Lactose Tolerance
NIH4Health

Lactose Tolerance in East Africa Points to Recent Evolution
The New York Times