Current research in my laboratory is focused on the fundamental mechanisms of ubiquitin signaling and regulation of mRNA transcription, with a focus on the role of histone ubiquitination in regulating transcription and chromatin dynamics. My group uses a combination of structural, biophysical and biochemical approaches to study enzyme complexes involved in these processes.

Awards and Achievements

  • Howard Hughes Medical Institute Investigator ( 1994 – 2014)
  • Fellow of the American Association for the Advancement of Science ( 2009)
  • Dorothy Crowfoot Hodgkin Award, Protein Society ( 2013)